Genetic Factors MUD

Trial Overview

Genetic factors affecting the outcome of unrelated stem cell transplantation. Primary Objective: To identify a significant correlation between genetic factors found in the donor or the recipients blood and transplant outcome. Secondary Objectives: To maintain a database of genetic typing to supplement the existing database kept by the registry

Inclusion criteria

  1. All donors who are provided by the Anthony Nolan Bone Marrow Trust (ANBMT)
  2. All patients to whom the stem cells are provided

Consultant Haematologist

Dr Maria Gilleece

Tel: 0113 2067956/ 2068433


Research Nurse

Anne Ewing

Tel: 0113 2067404


Other trials currently active for Transplant

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A Randomised Trial of the FLAMSA-BU CondItioning ReGimen in Patients with Acute Myeloid Leukaemia and Myelodysplasia UndeRgoing AllOgeneic Stem Cell Transplantation

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UK Haplo

A UK multicentre phase II study of haploidentical stem cell transplantation in patients with haematological malignancies

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Prophylactic Transfer of CD4 Lymphocytes (ProT4) A Multicentre randomised phase II study to evaluate the efficacy of prophylactic transfer of CD4 lymphocytes after T-cell depleted reduced intensity HLA-identical sibling transplantation for haematological cancer

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LenaRIC – Phase II study of the adjunctive use of Lenalidomide in patients undergoing reduced intensity conditioning allogenic transplantation for multiple myeloma.