Trial Overview

Molecular and functional characterisation of bone marrow function in normal subjects, myelodysplastic syndromes (MDS) and secondary disorders of haematopoiesis

Inclusion criteria

i) Patients with an abnormal blood count requiring investigation by blood and bone marrow sample.

ii) Patients known to have a blood disorder who are having a bone marrow sample taken as part of the assessment of that disorder.

Control subjects

Patients having elective orthopaedic surgery who have a normal blood count.


Exclusion criteria

i) Age < 18.


i) Age <18.

ii) On treatment likely to impair bone marrow function

iii) History of having had treatment likely to have impaired bone marrow function

Principal Investigator

Prof. David Bowen

Tel: 0113 2068481

E-mail: [email protected]

Research Nurse

Catherine Levy

Tel: 0113 2068577

E-mail: [email protected]

Other trials currently active for Myelodysplastic Syndromes

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Red blood cell transfusion thresholds and QoL in myelodysplastic syndromes: a pilot, feasibility study