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abvd act acute lymphoblastic leukaemia acute myelogenous leukemia (aml) acute myeloid leukaemia ade admire adoptive cellular therapy after 2 prior treatments alemtuzumab all allogeneic allogeneic stem cell transplant aml aml 17 angioimmunoblastic lymphoma antiviral therapy arctic autologous stem cell transplant autologous transplant autologus stem cell transplant azacitidine b-cell b-cell chronic lymphocytic leukaemia bevacizumab bexarotene blood cancers blood transfusions bone marrow
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The Clinical research facility is part of the NIHR and is funded by the Department of Health
There is a clear need to optimise the delivery of MTX in patients with PCNSL to improve current therapy, allow treatment of older patients and inform trial development. It is hoped that the planned use of glucarpidase as described in this protocol will allow safer and more effective drug delivery and open up further possibilities for future studies of combined therapy for this disease.